A native New Yorker, Anabelle's makeup career evolved through various opportunities in the cosmetics industry epicenter. Upon graduating from Hofstra University in 1992, she assisted the Beauty and Fashion Manager of Ladies' Home Journal magazine. In 1997, Anabelle moved on to Lancôme as Coordinator to the Associate Vice President of skincare marketing. Simultaneously, she studied makeup at Manhattan’s Learning Institute for Beauty Sciences.

In 1999, she embarked on her career as a Makeup Artist with the prestigious Laura Geller Makeup Studio in Manhattan. Anabelle ascended the ranks to become one of Laura's top artists for high-profile weddings and events. The latter included fashion shows, publicity events for Playboy magazine, and a guest appearance on the Montel Williams make-over episode. In addition, she appeared on camera as Laura Geller’s primary assistant during several of Laura’s QVC home-shopping showcases, which were hugely successful.

In June 2003, Anabelle launched her own freelance makeup business, Makeup by Anabelle LaGuardia. She continues to establish a loyal following of brides, socialites and photographers. Anabelle also serves as a consulting Makeup Artist to Lancôme’s Education Department, as well as their National Artistic Director, for the production of training videos.

Anabelle’s insight and advice, regarding current trends, is regularly sought after by highly circulated publications such as AM New York and The New York Observer. More recently, she has appeared on Lifetime TV’s Get Married program where she offered advice to brides on makeup for their weddings. Since January of 2008, Anabelle has been listed in the exclusive makeup directory for New York Magazine’s wedding issue.